Revised Second Edition | Available Now

All sterile compounding procedures in this courseware are aligned with
USP <797> (USP-NF 2023, Issue 1) and USP <800> (USP43-NF38).

Print and digital version of Sterile Compounding and Aseptic Technique, Second Edition

About the Courseware


  • Lisa McCartney, MEd, CPhT, PhTR
  • Brenda Jensen, CPhT, CNMT, MBA

This courseware provides instruction and training for the compounding of sterile parenteral preparations, a specialized, advanced practice of pharmacy technicians in hospitals, long-term care facilities, and home health care. This practice requires mastery of aseptic technique, or the procedures that avoid the introduction of pathogens into the sterile compounding environment and the preparations themselves.

Introducing the history, concepts, procedures, and revised USP <797>, this courseware leads students through a step-by-step exploratory or procedural lab that provides an opportunity for students to demonstrate their understanding of these major concepts.

Table of Contents

Chapter 1: Introduction to Sterile Compounding

Chapter 2: Medication Safety

Chapter 3: Law, Ethics, and Quality Assurance

Chapter 4: The Sterile Compounding Environment

Chapter 5: Sterile Compounding Supplies

Chapter 6: Medication Orders and Labeling

Chapter 7: Calculations for Sterile Compounding

Chapter 8: Hand Hygiene and Garbing

Chapter 9: Cleaning the Horizontal Laminar Airflow Workbench

Chapter 10: Large-Volume Parenteral Preparations

Chapter 11: Small-Volume Parenteral Preparations

Chapter 12: Ampule-Based Preparations

Chapter 13: Narcotic Analgesic Preparations

Chapter 14: Pediatric Preparations

Chapter 15: Parenteral Nutrition Preparations

Chapter 16: Hazardous Drug Preparation

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Woman using a syringe in full garb

Key Features

  • Aligns with revised USP <797> (USP-NF 2023, Issue 1) and USP <800> (USP43-NF38
  • Instructs and trains students in sterile compounding and aseptic technique and its real-world applications in a sterile compounding facility
  • Offers brief videos that demonstrate the nine procedural labs
  • Includes updated videos and photography
  • Offers supplemental reference materials in the appendices
  • Integrates with LTI-supported learning management systems, including Canvas, Blackboard, D2L, and Moodle

Cirrus™ 2.0 for Sterile Compounding and Aseptic Technique

Sterile Compounding and Aseptic Technique, powered by the Cirrus platform, integrates seamlessly with Blackboard, Canvas, D2L, and Moodle.

To strengthen student understanding, Cirrus provides interactive, independent learning experiences, including:

  • self-assessment opportunities
  • critical-thinking, application, and research activities
  • quizzes and exams
  • procedural lab videos

Course content is delivered in a series of scheduled assignments that report to a grade book, thus tracking student progress and achievement.

Sterile compounding happening under a hood

Instructor Resources in Cirrus

Utilize our free instructor resources that include:

  • course-planning guidelines
  • syllabus models
  • teaching hints and activities
  • quizzes and exams
  • answer keys
  • instructor rubrics
  • handouts
  • and more!

USP <797> Changes Incorporated in Second Edition

On November 1, 2022, the USP published a revision of USP General Chapter <797> Pharmaceutical Compounding—Sterile Preparations. In light of that, our second edition of Sterile Compounding and Aseptic Technique: Concepts, Training, and Assessment for Pharmacy Personnel aligns with this current, accepted USP <797> standard and, therefore, provides the necessary material to educate and train students in this specialized area of pharmacy practice. The revised USP <797> goes into effect November 1, 2023.

2nd Edition Changes

Working closely with the authors, we have created a free supplement to Sterile Compounding and Aseptic Technique, First Edition. This guide outlines key changes that will appear in the second edition that align with the new revised USP <797> (USPNF 2023, Issue 1) and USP <800> (USP43-NF38) standards.

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